Tetrahydropalmatine - Wikipedia
网页Tetrahydropalmatine (THP) is an isoquinoline alkaloid found in several different plant species, mainly in the genus Corydalis (Yan Hu Suo), [1][2] but also in other plants such as Stephania rotunda. [3] These plants have traditional uses in Chinese herbal medicine.
Tetrahydropalmatine | C21H25NO4 | CID 72301 - PubChem
网页Tetrahydropalmatine is a berberine alkaloid obtained by formal addition of two molecules of hydrogen to the pyridine ring of palmatine. It has a role as an adrenergic agent, a non-narcotic analgesic and a dopaminergic antagonist.
L -Tetrahydropalamatine: A Potential New Medication for the …
网页Levo-tetrahydropalmatine (l -THP) is an active constituent of herbal preparations containing plant species of the genera Stephania and Corydalis and has been approved and used in China for a number of clinical indications under the drug name Rotundine.
A Review of the Traditional Uses, Botany, Phytochemistry, …
网页2020年9月30日 · Tetrahydropalmatine alleviates cerebral ischemia/reperfusion injury by antagonizing free radicals and calcium ions and by regulating Ca 2+-ATPase activity. 65 It significantly reduces arrhythmias during ischemia/reperfusion injury and reduces lipid peroxides in the myocardium to prevent myocardial injury. 67 This compound significantly ...
Frontiers | A Comprehensive Review on the Chemical Properties, …
网页2022年4月25日 · Tetrahydropalmatine (THP, PubChem CID: 5417), with one chiral center, is a tetrahydroprotoberberine isoquinoline alkaloid and can be extracted from Stephania and Corydalis (Alasvand et al., 2019; Liu C. et al., 2019).
Tetrahydropalmatine: Orchestrating survival - ScienceDirect
网页2023年12月31日 · This study investigated tetrahydropalmatine (THP), a drug that inhibits autophagy and reduces apoptosis and oxidative stress, for its effects on flap survival. THP is an alkaloid extracted from Corydalis of Papaveraceae and has analgesic, soothing, and hypnotic effects.
Tetrahydropalmatine - an overview | ScienceDirect Topics
网页Tetrahydropalmatine (THP, 9, Fig. 2), also known as Rotundine, is an alkaloid pervasively present in the tubers of Corydalis yanhusuo (Papaveraceae). Numerous studies have highlighted its analgesic, tranquilizer and sedative effect in a long history of clinical practice.
Tetrahydropalmatine exerts analgesic effects by promoting …
网页2021年9月10日 · Tetrahydropalmatine (THP), an active component of traditional Chinese herbs derived from the corydalis Yanhusuo, has been reported to possess anti‐inflammatory and antinociceptive effects. 10,11 Although THP is a traditional analgesic medicine in the clinic, the mechanism of its antinociceptive effect is still unclear. Whether this ...
Tetrahydropalmatine has a therapeutic effect in a …
网页2019年12月12日 · Tetrahydropalmatine (Tet; Figure 1) is one of the main active components that is extracted from Rhizoma Corydalis, 8 which has been found to have anti-tumor 9 and anti-inflammatory pain effects. 10 A recent study has shown that Tet significantly inhibits inflammation responses and inducible nitric oxide synthase (iNOS) protein expression in ...
Tetrahydropalmatine - an overview | ScienceDirect Topics
网页Tetrahydropalmatine, protopine, and palmatine are the chemical moieties found in TCM herb, i.e., Rhizoma Corydalis Decumbentis. It is commonly used for the treatment of hemiplegia, rheumatoid arthritis, and infantile residual paralysis, to counteract the effects of dementia and hepatotoxicity, and for pain relief.