Dipeptidyl peptidase 4 inhibitors - Drugs.com
网页Dipeptidyl peptidase 4 (DPP-4) inhibitors are a class of medicine that lower high blood glucose levels and may be used in the treatment of type 2 diabetes. DPP-4 inhibitors slow the inactivation and degradation of GLP-1, a hormone involved …
Dipeptidyl peptidase 4 (DPP-4) inhibitors for the treatment ... - UpToDate
网页2023年4月27日 · This topic will review the mechanism of action and therapeutic utility of DPP-4 inhibitors for the treatment of type 2 diabetes mellitus. GLP-1 receptor agonists are discussed separately. General discussions of the initial management of blood glucose and the management of persistent hyperglycemia in adults with type 2 diabetes are also ...
Dipeptidyl Peptidase IV (DPP IV) Inhibitors - StatPearls - NCBI Bookshelf
网页2023年5月22日 · Dipeptidyl peptidase 4 (DPP-4) inhibitors are a group of antihyperglycemic medications used to manage type 2 diabetes mellitus, which is a significant risk factor for coronary disease, heart failure, stroke, and many other cardiovascular conditions. This activity reviews the various drugs in this group, indications, contraindications, activity ...
Dipeptidyl peptidase-4 - Wikipedia
网页Dipeptidyl peptidase-4 (DPP4 or DPPIV), also known as adenosine deaminase complexing protein 2 or CD26 (cluster of differentiation 26) is a protein that, in humans, is encoded by the DPP4 gene. [5] DPP4 is related to FAP, DPP8, and DPP9.
Information on Dipeptidyl Peptidase-4 (DPP-4) Inhibitors
网页DPP-4 inhibitors are a class of prescription medicines that are used with diet and exercise to control high blood sugar in adults with type 2 diabetes. Medicines in the DPP-4 inhibitor class...
二肽基肽酶-4 - 维基百科，自由的百科全书
网页二肽基肽酶-4 （dipeptidyl peptidase-4，DPP-4）又称 T细胞表面抗原CD26，是一种跨膜 丝氨酸多肽酶，分布广泛，作用多向 [1]。 可作为 二肽酶 水解多肽，从而调节肽类激素、神经肽、细胞因子和生长因子的活性，另可作为表面抗原与其他分子或蛋白共同合作，介导细胞与基质、细胞与细胞之间的相互作用。 在免疫激活、炎症反应和肿瘤发生中起到各种调节作用 [2]。 二肽基肽酶-4由 DPPP4 基因 编码 [3]。 DPP4与 ATRN 、 FAP 、 DPP8 和 DPP9 …
Dipeptidyl peptidase-4(DPP-4) inhibitors: promising new agents …
网页Dipeptidyl peptidase-4 (DPP-4) inhibitors constitute a novel class of anti-diabetic agents confirmed to improve glycemic control and preserve β-cell function in type 2 diabetes. Three major large-scale studies, EXAMINE, SAVOR-TIMI 53, and TECOS, have confirmed the cardiovascular safety profile of DPP-4 inhibitors.
Dipeptidyl peptidase 4 inhibitors in the treatment of type 2
网页2020年9月14日 · Dipeptidyl peptidase 4 inhibitors are now widely used in the treatment of patients with type 2 diabetes mellitus. This Review discusses the use of the five main dipeptidyl peptidase...
More than just an enzyme: Dipeptidyl peptidase-4 (DPP-4) and its ...
网页This review article discusses recent advances in the mechanism of dipeptidyl peptidase-4 (DPP-4) actions in renal diseases, especially diabetic kidney fibrosis, and summarizes anti-fibrotic functions of various DPP-4 inhibitors in diabetic nephropathy (DN).
Pharmacology, Physiology, and Mechanisms of Action of Dipeptidyl ...
网页2014年12月1日 · Dipeptidyl peptidase-4 (DPP4) is a widely expressed enzyme transducing actions through an anchored transmembrane molecule and a soluble circulating protein. Both membrane-associated and soluble DPP4 exert catalytic activity, cleaving proteins containing a position 2 alanine or proline.