The biology, function, and biomedical applications of exosomes
网页2020年2月2日 · Exosomes: A cell-to-cell transit system in the human body with pleiotropic functions. Exosomes are extracellular vesicles generated by all cells and they carry nucleic acids, proteins, lipids, and metabolites. They are mediators of near and long-distance intercellular communication in health and disease and affect various aspects of cell biology.
The biology, function, and biomedical applications of exosomes
网页2020年2月7日 · Exosomes are a type of extracellular vesicle that contain constituents (protein, DNA, and RNA) of the cells that secrete them. They are taken up by distant cells, where they can affect cell function and behavior.
Exosome | Definition, Size, & Function | Britannica
网页Exosome, nano-sized vesicle secreted from cells that contains any of various biomolecules, such as proteins or nucleic acids. Intercellular communication by exosomes plays a critical role in the regulation of physiological processes.
Q&A: What are exosomes, exactly? | BMC Biology | Full Text
网页2016年6月13日 · Exosomes are extracellular vesicles first described as such 30 years ago and since implicated in cell–cell communication and the transmission of disease states, and explored as a means of drug discovery. Yet fundamental questions about their biology remain unanswered.
Exosomes: a review of biologic function, diagnostic and targeted ...
网页2024年7月11日 · Exosomes are extracellular vesicles generated by all cells and they carry nucleic acids, proteins, lipids, and metabolites. They mediate the exchange of substances between cells,thereby affecting biological properties and activities of recipient cells.
Exosomes: biogenesis, biologic function and clinical potential
网页2019年2月15日 · In immune system, exosomes have an important function in immunoregulation, including antigen presentation, immune activation, immune suppression, and immune tolerance via exosome-mediated intercellular communication.
Exosomes: composition, biogenesis and function - Nature
网页2002年8月1日 · Exosomes are small membrane vesicles of endocytic origin that are secreted by most cells in culture. Interest in exosomes has intensified after their recent description in antigen-presenting cells...
Exosomes: biogenesis, biologic function and clinical potential
网页2019年2月15日 · Exosomes are nano-sized biovesicles released into surrounding body fluids upon fusion of multivesicular bodies and the plasma membrane. They were shown to carry cell-specific cargos of proteins, lipids, and genetic materials, and can be selectively taken up by neighboring or distant cells far from t ….
The exosome journey: from biogenesis to uptake and intracellular ...
网页2021年4月23日 · Exosomes are small extracellular vesicles secreted by all cell types playing intercellular communication roles in health and disease by transferring cellular cargoes such as functional proteins, metabolites and nucleic acids to recipient cells.
Exosome (vesicle) - Wikipedia
网页Exosomes, ranging in size from 30 to 150 nanometers, [1] are membrane-bound extracellular vesicles (EVs) that are produced in the endosomal compartment of most eukaryotic cells. [2] [3] [4] In multicellular organisms, exosomes and other EVs are found in biological fluids including saliva, blood, urine and cerebrospinal fluid. [5]EVs have …