Interleukin 3 - Wikipedia
网页Interleukin 3 (IL-3) is a cytokine that regulates the growth and differentiation of various blood cells. It is produced by activated T cells, monocytes, macrophages and stroma cells, and binds to a receptor with two subunits.
Interleukin 3 - an overview | ScienceDirect Topics
网页Learn about interleukin 3 (IL-3), a cytokine that stimulates the growth and survival of various progenitor cells and macrophages. Find chapters and articles from different books and journals that cover IL-3 and its role in immunology, inflammation, and neuroscience.
Interleukin - StatPearls - NCBI Bookshelf - National Center for ...
网页2022年8月22日 · Interleukin-3 (IL-3) T cells and stem cells make IL-3. It functions as a multilineage colony-stimulating factor. Interleukin-4 (IL-4) CD4+T cells (Th2) synthesize IL-4, and it acts on both B and T cells. It is a B-cell growth factor and …
IL-3: key orchestrator of inflammation - Frontiers
网页2024年6月3日 · IL-3 is a cytokine that regulates the survival, growth, differentiation and function of various immune and non-immune cells. It plays a role in host defense, autoimmunity and cancer, and is a potential target for therapy.
IL-3: key orchestrator of inflammation - PubMed
网页2024年6月13日 · Depending on the type of disease, the course of inflammation, the cell or the tissue involved, IL-3 promotes either pathologic inflammation or its resolution. Here, we describe the cell-specific functions of IL-3 and summarize its role in diseases.
Interleukin-3 gets a fresh start in the brain | Genes & Immunity
网页2023年12月8日 · Using multiple murine models and human tissue, we have identified interleukin-3 (IL-3) as a molecular messenger between the central nervous and peripheral immune systems that shapes brain...
Interleukin-3 in hematology and oncology: current state of
网页Interleukin (IL)-3 is a multipotent hematopoietic growth factor produced by activated T cells, monocytes/macrophages and stroma cells. The human IL-3 gene is located on chromosome 5 near segment 5q31. The high-affinity receptor for human IL …
Interleukin-3: Promises and Perspectives - PubMed
网页Interleukin-3 (IL-3) is a multipotent hematopoietic growth factor produced by activated T-cells, monocytes/macrophages and stroma cells. Human IL-3 gene is located on chromosome 5 near segment 5q31. The high affinity receptor for human IL-3 is composed of alpha and beta subunits.
Interleukin-3 amplifies acute inflammation and is a potential ... - Science
网页2015年3月13日 · Here we report that the cytokine interleukin-3 (IL-3) potentiates inflammation in sepsis. Using a mouse model of abdominal sepsis, we showed that innate response activator B cells produce IL-3, which induces myelopoiesis of Ly-6C high monocytes and neutrophils and fuels a cytokine storm.
Interleukin 3 - an overview | ScienceDirect Topics
网页Interleukin-3 (IL-3) is a cytokine of the beta common family—including IL-5 and granulocyte macrophage colony-stimulating factor—which stimulates proliferation and differentiation of a range of hematopoietic cell types through interaction with …
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