Despite the higher levels of DNA damage in polyploid cells, they showed greater resistance to cisplatin than diploid cells. Credit: Cell Death Discovery (2024). DOI: 10.1038/s41420-024-02206-w ...

(B) After treatment with the anti-cancer drug cisplatin, polyploid cells accumulated more DNA damage than diploid cells. The bright spots in the image represent DNA damage, visualized by microscopy.