These mechanisms, including those involving the tumor suppressor protein p53, are widely studied due to their critical role in disease. Through studies of proteins that regulate p53, scientists at St.
Corresponding author Richard Kriwacki, PhD, St. Jude Department of Structural Biology, investigated how the tumor suppressor p14ARF undergoes phase separation with nucleophosmin in the nucleolus to ...
IN recent years striking discoveries have been made regarding the origin and history of the nucleolus. It has como to be recognized that in every cell of a plant or animal species there is at ...
The École polytechnique fédérale de Lausanne (EPFL) is one of the two Swiss Federal Institutes of Technology and is located in Lausanne, Switzerland. The school was founded by the Swiss Federal ...
Chromosome 19 is shown in red whereas the nucleolus containing the gene-silencing machinery is in green. One can see close intermingling of chromosome 19 and the gene-silencing machinery at the ...
Did you know that every single living thing is made up of teeny, tiny unit structures? You have more than 75 trillion of them in your body – they’re called cells and they are amazing! Today we are ...
The images show the inside of the cell nucleus at an 8-cell stage (left) and at a later stage (right). Chromosome 19 is shown in red whereas the nucleolus containing the gene-silencing machinery is in ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Poly(ADP-ribose) polymerase 1 (PARP1) is one ...