“The diagnosis of Joseph’s tumor was a medulloblastoma, the most aggressive, grade 4 brain cancer among young children,” said Dr. Schneider. “In the United States, one in 300 children are diagnosed ...
SUFU modulates Sonic hedgehog (SHH) signaling and is frequently mutated in the B-subtype of SHH-driven medulloblastoma. The B-subtype occurs mostly in infants, is often metastatic, and lacks specific ...
Department of Neurology, Weill Institute for Neuroscience, University of California San Francisco, San Francisco, California Department of Psychiatry, Weill Institute for Neuroscience, University of ...