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亦敌亦友:自噬在HIV-1感染中的矛盾作用
Nef还可直接与Beclin-1结合,促进mTOR的激活并抑制 ... 这些化合物通过抑制mTORC1来诱导自噬。此外,还有ATP竞争性mTOR抑制剂和双重PI 3 K-mTOR抑制剂 ...
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