ATP-dependent RNA ligases join 3’-OH and 5’-PO 4 RNA termini via three nucleotidyl transfer steps similar to those of DNA ligases: (Step 1) ligase reacts with ATP to form a covalent ...

By targeting E3 ubiquitin ligase pathways, breeders may enhance plant defenses across species, bolstering food security ...

When resistance to or failure of hypomethylating agents (HMAs) occurs in acute myeloid leukemia (AML), depleting a ligase ...

if Codexis is unable to successfully develop and commercialize new technology such as its ECO Synthesis™ platform and its dsRNA ligase; Codexis dependence on a limited number of products and customers ...

The DNA repair and replication pathways converge on a common final step in which the continuity of the repaired DNA strand is restored by DNA ligase, an enzyme that converts nicks into phosphodiester ...

A research team at the Institute of Neurosciences of the University of Barcelona (UBneuro) has led a study describing a new ...

Spotlight Presentation to showcase four routes of synthesis of an approved siRNA therapeutic asset——Joint poster presentation with Bachem to ...

已报道的CBApts构建技术面临着一些挑战，包括使用T4连接酶，以及每个核酸适体末端需要13个额外的互补核苷。而新开发的环张力促进的炔烃-叠氮环 ...

"How is plant growth controlled?" and "What is the basis of variation in stress tolerance in plants?" were among the 125 most ...

In this sense, Malagelada points out that "if we can design inhibitors of the RTP801 protein—which we are currently working on—or preserve the activity of the tRNA ligase complex, we could ...

Revenue: Revenue for the three months ended September 30, 2024, increased to approximately $1,958,000 compared to $397,000 ...