Discover how preleukemic stem cells alter the bone marrow microenvironment, promoting leukemia growth. This study reveals key ...

It turns out our cells need the two copies working to produce enough PAX5, so these monoallelic mutations count as an ...

Over four hundred people, 80% of them being children under 14 years old, will be diagnosed with B-cell Acute Lymphoblastic ...

Rachel Rau, M.D. has expertise in the biology of hematologic malignancies with a current focus on the genomic and epigenetics of leukemogenesis and chemoresistance. Her lab’s recent work includes a ...

association of leukemogenesis with further genetic abnormalities. gretroviral and lentiviral vectors with a vector-specific nonrandom integration pattern in target cell genomes as revealed by ...

It turns out our cells need the two copies working to produce enough PAX5, so these monoallelic mutations count as an important driver of leukemogenesis. Furthermore, increasing PAX5 protein levels in ...

Unlike Its Paralog LEDGF/p75, HRP-2 Is Dispensable for MLL-R Leukemogenesis but Important for Leukemic Cell Survival. Cells. 2021 Jan 19;10(1):192. doi: 10.3390/cells10010192. PMID: 33477970; PMCID: ...

A new editorial paper was published in Oncotarget's Volume 15 on July 2, 2024, entitled, "DDX41 and its unique contribution to myeloid leukemogenesis." Relapsed/refractory acute myeloid leukemia ...

It turns out our cells need the two copies working to produce enough PAX5, so these monoallelic mutations count as an important driver of leukemogenesis. Furthermore, increasing PAX5 protein ...