Discover how preleukemic stem cells alter the bone marrow microenvironment, promoting leukemia growth. This study reveals key ...

5月21日，中国科学院上海营养与健康研究所王兰研究组在国际学术期刊Developmental Cell在线发表题为“SMARCA5 reprograms AKR1B1-mediated fructose metabolism to control leukemogenesis”的研究论文 5月21日，中国科学院上海营养与健康研究所王兰研究组在国际学术期刊Developmental Cell ...

The major focus of the Rau lab is to understand the molecular mechanisms that drive leukemogenesis and therapy resistance with the ultimate goal of translating these findings into better therapies for ...

Over four hundred people, 80% of them being children under 14 years old, will be diagnosed with B-cell Acute Lymphoblastic ...

association of leukemogenesis with further genetic abnormalities. gretroviral and lentiviral vectors with a vector-specific nonrandom integration pattern in target cell genomes as revealed by ...

It turns out our cells need the two copies working to produce enough PAX5, so these monoallelic mutations count as an ...

Applications are now open for our 2024/2025 PhD studentships. Below you will find a link to further information about our application process, our application portal and mailing list, should you wish ...

Rachel Rau, M.D. has expertise in the biology of hematologic malignancies with a current focus on the genomic and epigenetics of leukemogenesis and chemoresistance. Her lab’s recent work includes a ...

It turns out our cells need the two copies working to produce enough PAX5, so these monoallelic mutations count as an important driver of leukemogenesis. Furthermore, increasing PAX5 protein levels in ...