Overexpression and increased transcriptional activity of NFAT isoforms has been detected in various human solid tumours and cell lines, as well as haematological malignancies. This leads to the ...
This work is an important contribution to understanding the role of FGF signaling in the induction of primitive-like cells in a 2D system of human gastrulation. The authors provide compelling evidence ...
The tau gene produces six distinct isoforms, or versions, of the protein based on how the protein sequence is cut. Depending on which isoforms are affected, the accumulation of tau may present as ...
This important manuscript provides insights into the competition between Splicing Factor 1 (SF1) and Quaking (QKI) for binding at the ACUAA branch point sequence in a model intron, regulating exon ...
In order to map 3’ ends transcriptome-wide at single base resolution and to quantify the differential usage of 3’UTR isoforms between cell types, we have developed a computational and statistical ...
- Reprioritized resources to reduce costs and enhance focus on Nana-val’s development program in relapsed or refractory EBV-positive peripheral T-cell lymphoma (PTCL) - - On track to report data from ...