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16 天
抗体-药物偶联物(ADC)与糖尿病肾病
糖尿病肾病(DN)是全球肾脏疾病中发病率较高的一种。在DN的发展过程中,一个显著的特征是血管内皮生长因子(VEGF)和Gremlin介导血管内皮生长因子受体2(VEGFR2)在肾小球内的过度激活,导致内皮细胞通透性增加,从而导致蛋白尿。因此,使用单克隆抗体来 ...
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