▎药明康德内容团队编辑（来源：中国科学院昆明植物研究所）糖尿病足溃疡是糖尿病常见的高危并发症之一。目前，糖尿病足溃疡的临床治疗方法包括抗生素、生长因子、敷料和皮肤替代物等，但治疗效果有限。因此，糖尿病足溃疡在临床上亟需安全有效的新型治疗药物。中国科学院昆明植物研究所研究员吴明一团队聚焦于天然多糖的结 ...

A surprising finding by DiGabriele et al. 16 is that FGF-1 can bind heparin irrespective of the orientation of the glycosaminoglycan. In fact, as discussed below, the protomers within each FGF-1 ...

Tramiprosate is a glycosaminoglycan mimetic designed to bind to Aβ peptides, thereby stopping the formation of amyloid plaques. Owing to the short duration (3 months) of the tramiprosate Phase II ...

Turns out sea cucumbers contain high levels of a chemical called fucosylated glycosaminoglycan in their skin, which people across Asia have been using to treat joint problems like arthritis for ...

Lin Han obtained his BE degree from Tsinghua University in Beijing, P. R. China, and his PhD degree from the Massachusetts Institute of Technology in the area of Bio- and Polymeric Materials. After ...

The red module may be beneficial in aging via the preferential degranulation of mast cells; release of glucosamines, heparin (a glycosaminoglycan) and histamine, which induce vasodilatation ...

Recent research has uncovered a pivotal role for hyaluronic acid (aka hyaluronan, HA), a glycosaminoglycan found in the extracellular matrix of tissues like cartilage, in this immune modulation.

The Laboratory establishes cell lines from skin biopsies for enzyme studies. The Laboratory also provides enzyme and/or urine glycosaminoglycan studies for monitoring patients who have been treated ...

To her disbelief, Sanfillipo Syndrome, had symptoms that her daughter had been experiencing, which she thought were just ...

We are currently developing novel treatment strategies for CNS injuries based on the ability of HB-GAM and similar glycosaminoglycan-binding molecules to induce regenerative growth of neurites.

Teams of undergraduate students, faculty members and New Haven residents competed in New Haven Reads’ 12th annual Spelling ...

Thyroid autoimmune diseases like Graves disease are closely linked to thyroid eye disease and it is believed that antibodies directly affect the tissues of the orbit, leading to lymphocyte ...