The researchers evaluated the bioactivities of those compounds with α-glucosidase inhibition assay, a molecular docking experiment, and a glucose uptake experiment. They identified the diabetes ...

Oral antidiabetic medications can be separated by mechanism of action into two groups: hypoglycemics (sulfonylureas and meglitinides) and antihyperglycemics (biguanides and α-glucosidase inhibitors).

Through its Genzyme unit, Sanofi is one of the leading providers of drug therapies for Pompe disease, a glycogen storage disorder caused by a deficiency in the enzyme acid alfa glucosidase (GAA ...

B073Q157ZH It contains 500 mg of naturally occurring chlorogenic acid, which boosts the natural, plant-based green coffee extract and prevents the synthesis of the carbohydrate-digesting enzyme ...

Pompe disease is characterized by a deficiency of acid α-glucosidase (GAA). The GAA enzyme degrades lysosomal glycogen, and insufficient GAA activity causes glycogen to accumulate in various tissues.

Pistachio flavonoids, such as genistein, isoquercetin, quercetin, and rutin, inhibit an enzyme called α-glucosidase, which breaks down starch into glucose or blood sugar. This means that these ...

In addition, symptoms associated with Pompe's disease, including reduced heart, lung, and skeletal function, can be improved by treatment with acid ά-glucosidase enzyme. Protein augmentation ...

POMBILITI in combination with OPFOLDA is indicated for the treatment of adult patients with late-onset Pompe disease (lysosomal acid alpha-glucosidase [GAA] deficiency) weighing ≥40 kg and who are not ...

近日，国际生化与分子生物学Top期刊International Journal of Biological Macromolecules （CAS/JCR ...

"On the one hand, the polyphenols found in maple syrup could reduce the activity of an enzyme, intestinal alpha-glucosidase, which breaks down sucrose into glucose and fructose. As a result, fewer ...

11.3. The Advisory Committee recommended that avalglucosidase alfa for the treatment of late onset Pompe disease be funded with a medium priority.