Restoration of chemosensitivity in chemoresistant myeloma cells allows rechallenge of previously unsuccessful therapeutic agents, which might allow further disease control in patients with ...
When dominant-negative MITF was introduced into these cell lines, the chemosensitivity of the cells increased. The authors conclude that MITF is an essential lineage-survival factor in melanoma ...
Dauffenbach developed the Mosaic Blue assay for in vitro chemosensitivity testing of solid tumor explants, a method that is used to evaluate novel chemotherapeutic agents for activity prior to ...
accurate prognosis and specific chemosensitivity of lung and esophageal cancers. Current projects include using DNA methylation as a more accurate molecular indicator of lymph micrometases in a ...
These findings highlight BRT's ability to enhance Gem chemosensitivity by inhibiting Nrf2 signaling in PDAC; therefore, BRT may serve as a potential adjuvant therapy for PDAC.