Two research groups propose new synthetic strategies for making 'impossible' molecules, defying a 100-year-old bonding rule ...

The researchers created several different anti-Bredt olefins by making silyl precursors and then carrying out an elimination ...

Photocatalyst makes complex alkenes from acids, alkanes or alcohols, while a 'phase-pure' iron catalyst reduces unwanted ...

UCLA chemists have overturned a century-old rule in organic chemistry that limited molecular design by proving that ...

For a long time, scientists thought molecules could not have a carbon-carbon double bond at the bridge spot of a bicyclic molecule. This idea is called Bredt’s rule and it’s been in textbooks since ...

Stephen has a science degree with a major in physics, an arts degree with majors in English Literature and History and ...

UCLA chemists have found a big problem with a fundamental rule of organic chemistry that has been around for 100 years — it’s ...

"It destroys creativity when we have rules that supposedly can't be overcome," the California-based researchers said.

According to Bredt's rule, double bonds cannot exist at certain positions on organic molecules if the molecule's geometry deviates too far from what we learn in textbooks. This rule has constrained ...