Added glycine augments conversion of isovaleric acid (IVA) to isovalerylglycine (IVG) through glycine-N-acylase. The optimum glycine dosage for management of isovaleric acidemia is not known.

Arabinose was shown to serve as an effective inducer for induction of the lac-derived promoters in Escherichia coli using penicillin acylase (PAC) as a model protein. Upon the induction with a ...

Protein analysis and characterization is of critical importance to biopharmaceutical discovery research, development and manufacturing. Understanding the structure and function of therapeutic proteins ...

(2014) “Enhancement of Biological Reactions on Cell Surfaces via Macromolecular Crowding” Nature Communications, 5, Article number: 4683, DOI: 10.1038/ncomms5683 Kwan, D.H.,and Withers, S.G.* (2014) ...

Kopran also makes penicillin-G acylase an enzyme made through fermentation. It has technical collaborations with Gesellschaft Fur Biotechnologische Germany; Yuhan Co ...

This work reports the influence of different culture preservation methods on the production of penicillin G acylase (PGA) by Bacillus megaterium ATCC 14945. The initial stock culture, presenting PGA ...

Ras proteins play vital roles in numerous biological processes and Ras mutations are found in many human tumors. Understanding how Ras proteins are regulated is important for elucidating cell ...

The authors developed a versatile labeling strategy to allow visualization and identification of newly synthesized proteins in a cell population of interest. The approach enables cell-specific nascent ...

Candida-associated denture stomatitis is the most common form of oral candidal infection, with Candida albicans being the principal etiological agent. Candida adheres directly or via an intermediary ...