(1) Calcium greatly increased crystallization of monosodium urate in otherwise pure water, by enhancing both nucleation and growth. (2) Acid accelerated urate nucleation, both by its direct action and ...

Scientists from the University of California San Diego have uncovered a new cause of gout that could lead to more effective ...

Objectives To investigate the effects and mechanisms of action of high-density lipoproteins (HDL) in monosodium urate (MSU) crystal-induced inflammation —that is, gouty inflammation, in vivo. Methods ...

Various forms of crystals can result in different bladder stones, including magnesium ammonium phosphate (struvite), calcium ...

Merriman’s research interests also include outcomes in gout, especially severity and drug response. He also applies genetic epidemiological techniques to understanding the causal relationships in gout ...

Gout causes sudden flares of joint pain, which often arise during the nighttime, and in the big toe, though it may affect other joints including the ankles | Genetics And Genomics ...

The study finds gout is primarily genetic, debunking the myth of lifestyle causes. Discover effective treatments and the importance of genetic research. Gout is a genetic condition, with 96% of ...

Gout formation involves high urate levels, formation of urate crystals in the joints and immune system’s reaction to these crystals – genetics has a more significant role to play in this.

Without treatment, gout can reoccur several times a year and cause erosion and destruction in the affected joints. Urate crystals can also accumulate in the urinary tracts of people with gout, which ...

"People need to understand that while specific dietary factors, such as eating red meat, can trigger gout attacks, the ...