Immunotherapy, which enhances the immune system's T cell response to eliminate cancer cells, has emerged as a key approach in ...

Researchers say study offers proof-of-concept that targeting how T cells interact with metabolites in their environment can ...

Researchers found that methylmalonic acid treatment significantly reduced the activity of CD8 + T cells, an important component of the immune response to tumors. The study's results indicate that ...

Background: Integrin subunit alpha L (ITGAL) is crucial for activating CD8 + T cells through magnesium-mediated immune synapse formation and specific cytotoxicity. ITGAL might exert an important ...

A new study has found a surprising link between high levels of methylmalonic acid and the weakening of CD8+ T cells, shedding light on potential pathways through which aging may promote lung cancer ...

These interactions and signals can lead to transcriptional, functional, and phenotypic changes in TILs that diminish the host’s ability to eradicate the tumor. In addition to effector and memory CD8 + ...

A new study has found a surprising link between high levels of methylmalonic acid and the weakening of CD8+ T cells, shedding ...

The development of CAR-T technology in recent years has been a major milestone in the fight against cancer. These sort of ...

Researchers at Tel Aviv University (TAU) can add to that list their important discovery of a cancer mechanism that has been ...

including CD4/CD8 T cells, regulatory T cells, NK cells, and innate immune cells - Applications to a growing list of autoimmune conditions and cancer types - Effects and responses in treated patients ...