Meier and coauthors found that topotecan improved progression-free and overall survival compared with treosulfan in patients with recurrent ovarian cancer following platinum and taxane-based therapy.
6 Another trial has demonstrated superior overall survival for patients treated with topotecan and cisplatin compared with paclitaxel and cisplatin. 5 The GOG-204 trial demonstrated similar ...
Additionally, positive findings from trials like ADRIATIC (NCT03703297) and IMforte (NCT05091567) are further shaping ...
The study explored the effects of a new drug called berzosertib (M6620/VX970) combined with another drug, topotecan, to treat ...
topotecan, irinotecan, or gemcitabine). The trial was stopped early, following a unanimous recommendation by the Independent Data Monitoring Committee, based on the highly significant effect of ...
Current anticancer drugs like Camptothecin, Topotecan, and Irinotecan target Top1, but cancer cells often develop resistance ...
Background: Variable rates of HER2 protein overexpression and gene amplification have been reported in advanced ovarian cancers (AOC). Trastuzumab, tested only as a single agent, has been shown to ...
Health care providers need to provide a careful explanation of the procedure, why it is being done, what the possible findings might be, as well as what follow-up care might be necessary. A ...
John's wort, which is an herbal supplement that may be used to treat depression Certain cancer medicines such as topotecan Anticonvulsants such as carbamazepine (Carbatrol, Tegretol) Rifampin ...
Guidance on the use of capecitabine and tegafur with uracil for metastatic colorectal cancer TA61 27 May 2003 27 May 2003 Guidance on the use of drugs for early thrombolysis in the treatment of acute ...
Around 5.3 million people in England were given a NICE-recommended statin or ezetimibe by their GP to help reduce their cholesterol during 2023/24, the largest number on record and almost 900,000 more ...
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