Conclusion Our immunoepigenetic strategy harnesses IFNγ-mediated network to augment the cancer-immunity cycle, revealing a self-reinforcing STAT1-GSDME pyroptotic circuitry as the mechanistic basis ...

The Teachers Service Commission (TSC) has announced that it will recruit 20,000 teachers for junior secondary schools, amid a nationwide shortage of tutors. TSC is set to conduct another recruitment ...

The Teachers Service Commission (TSC) will next week advertise a fresh round of recruitment of 20,000 teachers on contract for junior schools, giving an opportunity for hundreds of thousands of ...

Given recent evidence that pyroptosis, as a new form of programmed cell death, is induced by caspase-3-dependent GSDME (gasdermin E) cleavage, we hypothesized that cathepsin L might promote PH through ...

Use the Tableau Server Client (TSC) library to increase your productivity as you interact with the Tableau Server REST API. With the TSC library you can do almost everything that you can do with the ...

Here, we demonstrated that ZIKV causes the pyroptosis of placental cells by activating the executor gasdermin E (GSDME) in vitro and in vivo. Mechanistically, TNF-α release is induced upon the ...