依沃西单抗（AK112）是由康方生物研发的人源化 IgG1-ScFv 结构的双特异性单克隆抗体，是采用 Tetrabody 双特异性抗体开发技术设计的创新性四价结构，可同时靶向 PD-1 和 VEGF-A，发挥免疫和抗血管生成的双重治疗作用。今年 5 月，依沃西单抗已获国家药品监督管理局 ...

The investigational new drug application for VNX-101, a gene therapy aimed at treating CD19-positive acute lymphoblastic ...

These toxins provide new tools for precision cancer medicine, bringing us closer to the elusive “magic bullet.” In addition, ...

Ainnocence Inc., a leader in AI-driven biotech solutions, is proud to announce the launch of CellulaAI™, an innovative AI ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. DNA i-motif structures are formed in the ...

Protein L配基与抗体kappa轻链的可变区有很强的亲和性，所以Diamond Protein L适用于从大批量细胞培养液中捕获各种不同大小的抗体片段，如 F(ab')2、Fab、单链可变片段（scFv）和半抗。 • 结合缓冲液：通常采用中性缓冲液，如：20mM PB，0.15M NaCl，pH7.2 • 洗脱缓冲液 ...

Additional claims describe the antibodies as potentially human, including various forms such as purified antibodies, single-chain antibodies, and fragments like Fab and scFv. Furthermore, the patent ...

Journal of Nuclear Medicine August 2024, jnumed.124.267685; DOI: https://doi.org/10.2967/jnumed.124.267685 ...

吸入式肺靶向疗法治疗IPF的示意图 基于上述iLNP-HP08 LOOP 递送载体，研究人员进一步利用其负载编码IL-11单链抗体（scFv）mRNA得到scFv@iLNP-HP08 LOOP ，从而成功开发出一种mRNA介导的抗体吸入疗法。上述scFv@iLNP-HP08 LOOP 经振动网筛雾化器递送到小鼠肺部后，能够有效沉积 ...