GTP is also a substrate for the synthesis of RNA during transcription. Purine metabolism involves the synthesis and breakdown of purine nucleotides in cells. Disorders of purine metabolism can lead to ...

The purine/purinergic system has emerged as a fundamental regulator of cellular communication, influencing various physiological processes such as metabolism, energy balance, and signal transduction.

By analyzing the blood and cerebrospinal fluid (CSF) of the patients, researchers have discovered critical impairments in purine metabolism and the recycling of adenosine triphosphate (ATP)-;the ...

This pathway involves the conversion of simple precursor molecules ... These drugs interfere with DNA synthesis and replication, leading to the death of rapidly dividing cancer cells. Pyrimidine ...