When it comes to supplying their purine needs, cancer cells may use salvaged metabolites, according to a study in mice.

The salvage pathway recycles preformed nucleobases and nucleosides from the breakdown of nucleic acids and nucleotides. This pathway is more energy-efficient than the de novo pathway and helps ...

Parkinson's disease (PD), the second most common neurodegenerative disorder globally, has long baffled scientists with its ...

A recent study from the School of Medicine at Fujita Health University has brought new insights into the metabolic ...

A new study has revealed critical metabolic impairments in Parkinson’s disease (PD), focusing on purine metabolism and ATP ...

[1,8] In mammalian cells there are at least four major pathways: first, a simple reversal of the damage; second, nucleotide excision repair (NER), including mismatch and transcription-coupled ...

For the current study, the researchers were interested in determining whether single nucleotide polymorphisms (SNPs) linked to gut microbiota pathway abundance affect insomnia risk. They also ...

The Johns Hopkins team also found that while most photoreceptors using the ciliary signaling pathway use a particular cyclic nucleotide, cGMP, as the signaling messenger, ipRGCs use another ...

Researchers recently discovered that patients with Parkinson's disease exhibit lower levels of uric acid and impaired energy recycling. It challenges previous beliefs about uric acid's role in the ...

Parkinson's disease (PD), the second most common neurodegenerative disorder globally, has long baffled scientists with its progressive nature and debilitating effects on motor function.

Bemnifosbuvir, an oral nucleotide RNA-dependent RNA polymerase ... Through the activation pathway to AT-9010, HCV RNA synthesis is halted through RNA chain termination, and SARS-CoV-2 RNA ...