Lack of NaV1.7 activity leads to the inability to sense pain, whereas NaV1.7 gain of function leads to severe pain. Modulation of NaV1.7, therefore, should be an effective mechanism for decreasing ...
Neuropathy can cause numbness, tingling, burning, extreme sensitivity, or sharp pain in your ... narrow), or a pinched nerve. Once a correct diagnosis is established, treatment and prevention ...
Vertex Pharmaceuticals Incorporated (Nasdaq: VRTX) today announced results from its Phase 2 study of suzetrigine, an investigational, oral, highly selective NaV1.8 pain signal inhibitor in people with ...