Researchers have created a highly detailed cellular map of Alzheimer’s disease progression, revealing new insights into the ...

Research from the College of Medicine provides promising insights into delaying the progression of Alzheimer’s disease for ...

Analysis of human brain tissue revealed differences in how immune cells behave in brains with Alzheimer's disease compared to ...

Penn Ovarian Cancer Research Center and Basser Center for BRCA, University of Pennsylvania, Perelman School of Medicine, Philadelphia, United States ...

POLK expression in neurons and report an important observation that POLK exhibits an age-dependent change in subcellular localization, from the nucleus in young tissue to the cytoplasm in old tissue.

Researchers have developed a promising nasal spray therapy targeting neuroinflammation in Alzheimer’s disease, potentially ...

A new therapy may delay Alzheimer's disease progression by years, according to a study by researchers at Texas A&M University ...

In healthy brains, immune cells called microglia patrol for damage, clearing away debris and harmful proteins. But in the presence of the APOE4 protein-;the most important genetic risk factor for ...

“Together, these results suggest that microglia are being activated by human neuron–produced APOE4 and, in turn, are ...