ukaachen.de Conclusions MDR2-associated cholestasis triggers intestinal dysbiosis. In turn, translocation of endotoxin into the portal vein and subsequent NLRP3 inflammasome activation contribute to ...

NLRP3 inflammasomes are an important component of intrinsic immunity, but the role of NLRP3 inflammasome activation is currently controversial. This study aims to investigate the role and mechanisms ...

CVN293 was generally well-tolerated in healthy volunteers for up to 14-days of continuous dosingDose-dependent exposure was ...

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In preparation for an IND submission for Inflammasome ASC Inhibitor IC 100 and a subsequent Phase 1 trial in healthy ... of ...

We are pleased to announce the progress that ZyVersa has made toward achieving our key near-term development milestones,” stated ...

Fructose, the most common food sweetener, is widely used in processed sugary beverages, candies, and baked goods. Excessive ...

Ipsen to present new data on elafibranor at The Liver Meeting® 2024Launch of Iqirvo® (elafibranor)1 on track with ...

Kodiak Sciences Inc. , today reported business highlights and financial results for the quarter ended September 30, 2024. "In the third quarter we hosted an Investor R&D Day in New York," said Victor ...

Nutritional supplements are any dietary supplement that is intended to provide nutrients that may otherwise not be consumed in sufficient quantities; for example, vitamins, minerals, proteins ...