The TT genotype appears to predispose to CRC that is MSI+. This may reflect the involvement of aberrant DNA methylation frequently associated with MSI+. The 844ins68 CBS polymorphism may protect ...

For example, researchers have found mutations of the MTHFR gene, or methylenetetrahydrofolate reductase, to be linked to conditions like depression, bipolar disorder, certain cancers, and high ...

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Systemic sclerosis (SSc) is a rare and highly heterogeneous chronic autoimmune disease characterized by multi-organ and tissue fibrosis, often accompanied by a poor prognosis and high mortality rates.

Although no specific data to support pharmacogenetic-related birth defects were found for the NSAIDs, paroxetine and fluoxetine, it might be expected that polymorphisms modify their teratogenic ...

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed ...

We also estimated gestational FA supplementation via surveys and genotyped the maternal MTHFR 677C>T single nucleotide polymorphism (SNP). We estimated the confounder-adjusted associations between ...

A new study shows that high-potency cannabis use leaves distinct marks on DNA, potentially identifying those at risk for psychosis. These findings offer new insights into how cannabis affects mental ...

Individuals with MTHFR gene mutations often depend on Methylfolate supplements. These genetic changes can lead to a lack of folate, an essential nutrient that plays a crucial role in various body ...