Cite this: Targeting Ligand-gated Ion Channels in Neurology and Psychiatry: Is Pharmacological Promiscuity an Obstacle or an Opportunity? - Medscape - Mar 02, 2010.

The silk moth’s mouth and brain contain the receptor. Because it is a ligand-gated receptor, activation occurs only in response to the ligand the molecule that is able to bind to it attaches.

it will take no more than a few milliseconds for the postsynaptic ligand-gated channels to open and trigger a cascade of electrochemical signaling pathways. Information transmitted by synaptic ...

Topics include membrane transport and diffusion, the biophysics of excitable membranes, the gating of voltage and ligand-gated ion channels, intracellular calcium signalling, and electrical bursting ...

This manuscript introduces DendroTweaks, a useful web application and Python library that, compared to existing modeling tools, eases interactive graphical exploration, development, and validation of ...

It can be used for a wide range of analyses, including kinetic analysis, titers IgG and other proteins, reagent quantification, crude antibody screening, epitope binning/mapping, ligand binding assays ...

Ongoing research projects include retinoids as chemopreventive and chemotherapeutic agents, inhibitors of influenza neuraminidase as orally active flu drugs, inhibitors of NAD synthetase as broad ...

Pregabalin binds with high affinity to the alpha2-delta site (an auxiliary subunit of voltage-gated calcium channels) in central nervous system tissues. Although the mechanism of action of ...

秋风送爽，丹桂飘香。近日（9月19日-22日），由中华医学会、中华医学会神经病学分会主办，河南省医学会承办的“中华医学会第二十七次神经病学学术会议”在美丽的郑州顺利召开。国内外知名专家学者齐聚，共享学术饕餮盛宴。神经病理性疼痛（NP）指由躯体感觉系统 ...

“It had 10-foot-high ceilings on the ground floor and second floor, and it was gated [off] by the current owners, so it’s like a mini Georgian estate.” “It’s in a wonderful school ...