Discover the impact of hypereosinophilia on heart health, focusing on eosinophilic heart disease (EHD) and its mechanisms.

Eosinophils are white blood cells that play an essential role in the immune system, specifically in fighting diseases and ...

In the course of the ALS development program, however, dexpramipexole was observed to produce a significant and targeted depletion of eosinophils in the blood of ALS patients 4. Eosinophils are ...

This disruption leads to a boost in eosinophils in the lungs. Eosinophils are immune cells that hinder the function of other cells responsible for clearing pathogens from the lungs. In a mouse model ...

团队首先利用Pac1敲除小鼠和多种实验性哮喘模型发现PAC1的缺失可以显著加重II型炎症。进一步地利用过继转移、骨髓嵌合小鼠和条件性基因敲除小鼠等模型，明确了PAC1通过细胞内在机制限制ILC2s的应答，主要表现为抑制其增殖和分泌IL-13。在机制上 ...

The introduction of Dupixent changes the treatment landscape by specifically targeting type 2 inflammation pathways (IL-4 and ...

Eosinophilic asthma (also known as e-asthma or eos asthma) is a severe form of asthma that causes high levels of eosinophils in the lung tissue, blood, and mucus. Eosinophils are a type of immune ...

Researchers from Johns Hopkins Medicine and Yale University have collaborated on the development and application of a ...

Amali Samarasinghe, PhD, associate professor in the Department of Pediatrics at UT Health Science Center, describes herself as an aficionada of the alternative hypothesis. “I have a passion to uncover ...

EMA approves Dupixent to treat eosinophilic esophagitis in children as young as one year: Paris Thursday, November 7, 2024, 14:00 Hrs [IST] The European Medicines Agency has appro ...

Eupraxia Pharmaceuticals Inc. ("Eupraxia" or the "Company") (TSX: EPRX) (NASDAQ: EPRX), a clinical-stage biotechnology ...