In The Lancet Respiratory Medicine, Olivier Sitbon and colleagues1 present the results of a randomised, phase 2b clinical trial (ELEVATE-2) that compared the safety and efficacy of pulmonary arterial ...

Emerging research has linked COVID-19 to joint pain and osteoarthritis, but the precise mechanisms behind this connection and ...

The European approval comes months after the FDA’s approval of the first-of-its-kind treatment for pulmonary arterial ...

BQ-3020 是一种内皮素受体 (endothelin receptor) (ETBreceptor) 激动剂，取代[125I]ET-1 与猪小脑 ETB 受体结合，IC50 值为 0.2 nM。BQ-3020 引起兔肺动脉血管收缩和猪膀胱颈松弛，可用于心血管疾病研究。 BQ-3020是一种内皮素受体（ETB receptor）激动剂，能够取代125IET-1与猪小脑ETB ...

Two abstracts win the prestigious AHA 2024 Paul Dudley White International Scholar Award Allschwil, Switzerland - September 5, 2024Idorsia Ltd (SIX: IDIA) today announced that new data on aprocitentan ...

Two abstracts win the prestigious AHA 2024 Paul Dudley White International Scholar Award Allschwil, Switzerland – September 5 ...

The Endothelin B Receptor pipeline drugs market research report outlays comprehensive information on the Endothelin B Receptor targeted therapeutics, complete with analysis by indications, stage of ...

The key targets in the Alport Syndrome pipeline products market include Endothelin 1 Receptor (Endothelin A Receptor or EDNRA), Dystrophin (DMD), and Free Radical. Alport syndrome is a genetic ...

Endothelin 1 (swine, human) 是具有人和猪内皮素1序列的合成肽，是有效的内源性血管收缩剂。Endothelin 1 通过两种类型受体ETA和ETB发挥作用。 Endothelin-1（ET-1），无论是在人类还是猪体内，都是一种高度保守且具有显著生物活性的多肽，属于内皮素家族的关键成员。

The mechanisms behind this decline are not fully understood. While excessive production of endothelin 1 (ET-1), a potent vasoconstrictor, is linked to many diseases that increase with age, the role of ...

Louis, USA Hope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, USA The manuscript by Feng et al. reported that the Endothelin B receptor (ETBR) expressed by ...