These findings suggest that KIR2DS2-positive (KIR2DS2+) natural killer (NK) cells could be an attractive therapeutic target ...

By co-localization studies, the researchers showed that only a few of the IL-17A-positive cells in the inflamed synovium were T cells, as most of them were negative for the T cell markers CD3 ...

Inter-organelle communication via the formation of membrane contact sites (MCS) is essential for cell homeostasis. Bacterial pathogens residing in membrane bound vacuoles have exploited this ...

Scientists at Pohang University of Science and Technology (POSTECH) and ShanghaiTech University have achieved a breakthrough ...

The CAR-T cell therapy Aucatzyl was approved for relapsed or refractory B-cell precursor acute lymphoblastic leukemia based ...

1Centre de Recherche en Cancérologie de Marseille, INSERM U1068, CNRS UMR7258, Aix Marseille Université U105, Institut Paoli Calmettes, Marseille, France. 4Institut Paoli-Calmettes, Marseille, France.

Safety concerns include low levels of grade 3 cytokine release syndrome and immune effector cell-associated neurotoxicity ...

Bristol Myers Squibb has linked its CD19-directed CAR-T cell therapy to sustained clinical responses in people with systemic ...

The CAR-T cell therapy Carvykti has been shown to be effective among patients outside the confines of a clinical trial.