or blood cancer. CD4/CD8 ratio testing is typically done regularly, from the first sign of an illness, to monitor immune response. Okoye AA, Picker LJ. CD4(+) T-cell depletion in HIV infection: ...

T cells are white blood cells that are important for adaptive immunity. They have unique cell surface receptors that are generated by randomly assorting genes. These receptors allow T cells to ...

A new phase 1 trial demonstrates the safety and effectiveness of personalized neoantigen DNA vaccines, showing promising ...

The development of CAR-T cell therapy marks a major breakthrough in cancer treatment. These “living drugs” are T-cells genetically engineered to spread through the body, identify, and destroy cancer ...

Researchers from the Josep Carreras Leukaemia Research Institute have found that the efficacy of varni-cel, a CAR-T infusion ...

Researchers at Winship Cancer Institute of Emory University have identified a novel type of immune cell, called the stem-like CD4 T cell, that plays a pivotal role in anti-tumor immunity.

The development of CAR-T technology in recent years has been a major milestone in the fight against cancer. These sort of ...

The vaccine boosted the power of cancer-fighting immune cells, but only if the tumors were in an early stage and not advanced state. The vaccine was previously tested in human clinical trials for ...

“The impaired numbers of CD3 + T cell may contribute to a weakened anti-tumor response, potentially leading to a poorer prognosis ... The number of IgG, B-lymphocytes, CD4/CD8, CD4 + T-lymphocytes, ...

including CD4/CD8 T cells, regulatory T cells, NK cells, and innate immune cells - Applications to a growing list of autoimmune conditions and cancer types - Effects and responses in treated patients ...

Both published and newer data suggests that DNase I impedes neutrophil tumor infiltration, promotes CD4 and CD8 T cell infiltration, and enhances intratumoral T cell activation. DNase I plus -CTLA-4 ...