Ovarian tumors are infiltrated by both effector (CD4+CD25-) T cells and by an excess of TREG cells (CD4+CD25+). These TREG cells impede the function of the effectors in combating the tumor.

New research shows that blood-based immunophenotyping can enhance rheumatoid arthritis treatment by identifying immune ...

Surface proteins and cytokines of lung T cells were analyzed by flow cytometry using antibodies against CD3 ... These results indicate that chronic tobacco stimulation primarily leads to increased ...

T-Mobile is the third-largest wireless carrier in the United States, with its popularity largely down to its network coverage and the wide range of tempting offers available. They span from T ...

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这类PD1 + TCF + CD4 + T细胞虽然原本可以向效应T细胞等不同方向分化，但在同为CD4 + T细胞的Tregs约束下，它们分化产生的基本只能是Tregs；只有当Tregs被 ...

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Interestingly, the final differentiation of both T and B cells involves a BLIMP1-independent clonal-expansion phase, followed by the production of short-lived effector cells that require BLIMP1 to ...

Activated and naive T cells expressed minimal-to-undetectable levels of oncofetal CS and the expression was ~20× lower than that detected in UM-UC-3 cells (Fig. 1A). The concentrations of the ...

Using flow cytometry together with mRNA expression analysis for identifying T CD4+ cell subsets, the authors found that the accelerated aortic inflammation induced by CCR4 deficiency correlated with ...