Cryptococcal meningitis (CM) is the leading cause of fungal meningitis in humans worldwide, with the largest disease burden reported in Africa (1). The majority of CM cases are caused by members of ...

The inducible innate immune response to infection requires a concerted process of gene expression that is regulated at multiple levels. Most global analyses of the innate immune response have focused ...

RbpA and CarD are essential transcription regulators in mycobacteria. Mechanistic analyses of promoter open complex (RPo) formation establish that RbpA and CarD cooperatively stimulate formation of an ...