Antigen processing and presentation is the process by which protein antigen is ingested by an antigen-presenting cell (APC), partially digested into peptide fragments and then displayed on the ...

Background Genomic screening uncovered interferon-gamma (IFNγ) pathway defects in tumours refractory to immune checkpoint blockade (ICB). However, its non-mutational regulation and reversibility for ...

which renders the payload inert and is cleaved only within the tumor by the action of Fibroblast Activation Protein, or FAP, expressed in the cancer associated fibroblasts in the TME. The pre ...

By targeting various components of the TME—such as immune suppression, stromal interactions, hypoxia, and antigen presentation, combination therapies can enhance the effectiveness of immunotherapy and ...

We hypothesized cardiac fibroblast (CFB) AHR and its agonism by L-Kyn prevent the pro-fibrotic and pro-inflammatory activity of CFBs in experimental HF. To investigate the role of L-Kyn agonism of CFB ...

Using The Presentation Experience codes is the best way to accumulate a large number of points and gems in the title. Additionally, the Roblox game offers boosts to help you increase the rate of ...

Analysis of the immune tumour microenvironment at the two locations suggests that fast peritoneal tumour growth in the immunocompromised setting is abrogated in immunocompetent animals due to ...

New technologies are enabling discoveries that advance our understanding of how tumors develop, evade the immune system, and progress. This virtual conference brings together research professionals, ...