Was it from rolling your ankle in the backyard yesterday? Or could it be tendonitis from the extra miles you ran this week?

Gout causes sudden flares of joint pain, which often arise during the nighttime, and in the big toe, though it may affect other joints including the ankles | Genetics And Genomics ...

Discover the causes, symptoms, and treatment options for gout—a painful form of arthritis predominantly affecting men.

Medically reviewed by Cara Beth Lee, MD Fact checked by Khara Scheppmann Swelling in the ankles and feet is a common problem.

To further explore the consequences of IL-1 blockade, the investigators developed a new acute gout model by use of intra-articular injection of MSU crystals into the ankle joint of mice.