We have been exploring the potential of the neuromodulator, adenosine, to reduce excessive dopamine signaling that contributes to the development and persistence of psychostimulant abuse. Dopamine’s ...

Exploration of adenosine mechanism revealed adenosine receptors as a potentially useful target of therapy in RA.

Exploration of adenosine mechanism revealed adenosine receptors as a potentially useful target of therapy in RA.

Researchers found that caffeine blocks alcohol’s ability to increase dopamine in brain reward areas, potentially reducing ...

The authors conclude that nonsynaptic release of ATP and subsequent activation of adenosine A 1 receptors contributes to suppression of thalamic activity and tremor, alone and during DBS ...

Aurigene Oncology Ltd. has divulged compounds acting as dual antagonists of adenosine receptor A2A (ADORA2A) and programmed cell death 1 ligand 1 (CD274; PD-L1) reported to be useful for the treatment ...

This is because the body develops a tolerance to caffeine. Caffeine binds to a receptor in the brain used by adenosine. The binding of caffeine to these receptors causes the body to delay the onset of ...