We have been exploring the potential of the neuromodulator, adenosine, to reduce excessive dopamine signaling that contributes to the development and persistence of psychostimulant abuse. Dopamine’s ...
Consider adenosine A 2A receptor antagonists, for example, which are being evaluated as an adjuvant therapy to L-dopa or D 2 receptor agonists for Parkinson's disease, based on the evidence of ...
Exploration of adenosine mechanism revealed adenosine receptors as a potentially useful target of therapy in RA. Principal signaling pathways activated by adenosine receptors. AC: Adenylate ...
Caffeine's stimulating effects can paradoxically lead to sleepiness due to tolerance, adenosine receptor changes, and individual metabolic differences.