and AMP-activated protein kinase (AMPK) pathways. SIRT1 also participates in inflammatory signaling regulation in macrophages and DC as well as modulating the secretion of inflammatory cytokines.

In the current investigation, we have studied several conditions that increase metabolic stress to ascertain whether they lead to an increase in isoform-specific AMPK activity in skeletal muscle ...

VShred is a health and fitness brand based in Las Vegas that was set up in 2015. Since then, the brand has risen to become ...

Plantsulin ignites excitement in the health industry with its promise of natural blood sugar regulation. Wellness trends ...

Brown adipocytes are increasingly recognized as a promising therapeutic target for metabolic disorders ... The study demonstrates that activation of brown adipocytes deprives leukaemia cells ...

Repurposing of a drug designed for pain relief can quickly and reversibly slow biochemical and metabolic activities in cells and organs and could facilitate organ transplantation and prevent tissue ...

A study led by Manuel Vázquez Carrera, group leader at the Diabetes and Associated Metabolic Diseases Networking Biomedical Research Centre (CIBERDEM) at the University of Barcelona, reveals ...

You can create a release to package software, along with release notes and links to binary files, for other people to use. Learn more about releases in our docs.

Richard J. Johnson; Takahiko Nakagawa; L. Gabriela Sanchez-Lozada; Mohamed Shafiu; Shikha Sundaram; Myphuong Le; Takuji Ishimoto; Yuri Y. Sautin; Miguel A. Lanaspa ...

This suggests that pharmacologic, stress-independent activation of the ISR represents a potential strategy to mitigate pathologic mitochondrial fragmentation associated with human disease. Here, we ...