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中国科学院
22 天
微生物所设计出新型猴痘mRNA疫苗
该疫苗在小鼠中可诱导出高效的体液免疫与细胞免疫,维持抗体水平在免疫近6个月后基本不变,实现了致死剂量痘苗病毒攻毒后对小鼠的完全保护,并可在猴痘病毒攻毒后降低小鼠多个器官中的病毒载量。相比之下,同样痘苗病毒剂量下,接种痘苗天坛株减毒活 ...
大众网
2 个月
首款国产猴痘疫苗进入临床,对新变异株有用吗?
中国境内尚无猴痘疫苗上市。 首款获批临床的国产猴痘疫苗技术路径与目前全球大范围使用的丹麦公司Bavarian Nordic研制的JYNNEOS猴痘疫苗一致,是基于复制缺陷型痘苗病毒MVA株开发的,其安全性和有效性已经得到临床的充分论证。 “MVA疫苗最早是用来预防天花的 ...
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