Background Pulmonary microvasculature alterations are implicated in emphysema pathogenesis, but the association between ...

1 Department of General Practice, Division of Public Health, Academic Medical Center, University of Amsterdam, The Netherlands 2 Department of Clinical Epidemiology, Leiden University Medical Centre, ...

Rationale There are no population-based studies from sub-Saharan Africa describing longitudinal lung function in adults. Objectives To explore the lung function trajectories and their determinants, ...

3 Centre for Clinical Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada Correspondence to Dr Pierre Ernst, Centre for Clinical Epidemiology, ...

We used data from 11 577 children in the UK Millennium Cohort Study, collected at approximately 14 years of age (early teens), to assess characteristics associated with smoking, and generated regional ...

Acute respiratory distress syndrome (ARDS) is a neutrophil-dominant disorder with no effective pharmacological therapies. While the cyclin-dependent kinase inhibitor AT7519 induces neutrophil ...

1 Department of Palliative Medicine, The North London Hospice and Barnet and Chase Farm Hospitals NHS Trust, London N12 8TF, UK 2 Department of Palliative Medicine, Bristol Haematology and Oncology ...

Background: In adults, viral causes of community-acquired pneumonia (CAP) are poorly characterised. The aims of this study were to characterise the viral aetiology of CAP in adults by using an ...

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A structural and metabolic framework for classifying pre-clinical tuberculosis infection phenotypes using 18F-FDG PET-CT: a prospective cohort analysis following M. tuberculosis exposure ...