Numerous substances induce oxidative stress, including carbon tetrachloride, TBH, ethanol, paracetamol (acetaminophen) and phenylhydrazine. It has been shown in rats that silibinin protects ...

Silymarin is not soluble in water and is usually administered in capsules as a standard extract (70 to 80% silymarin). Silibinin and other components of silymarin are rapidly conjugated with ...