In rat liver nuclei there are two RNA polymerase activities. One polymerase (I) is probably localized in the nucleolus and one (II) in the nucleoplasm.

Chromosome 19 is shown in red whereas the nucleolus containing the gene-silencing machinery is in green. One can see close intermingling of chromosome 19 and the gene-silencing machinery at the ...

A critical transition in early human development is regulated not by our own genes, but by DNA elements called transposons that can move around the genome, Sinai Health researchers have found ...

The images show the inside of the cell nucleus at an 8-cell stage (left) and at a later stage (right). Chromosome 19 is shown in red whereas the nucleolus containing the gene-silencing machinery is in ...

Here, the authors identify that the snoRNA SNORD88B drives self-renewal of liver CSCs and liver tumorigenesis through promoting the nucleolar shuttle protein WRN retention in the nucleolus and ...

Translational Sciences and Therapeutics Division, Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA Department of Biochemistry and Department of Medicine, University of Washington, ...

Ribosomes themselves are assembled in a structure called the nucleolus, which is located inside the nucleus of the cell. And it is stress in this nucleolus that appears to significantly contribute to ...

Ribosomal RNA transcription mediated by RNA polymerase I represents the rate-limiting step in ribosome biogenesis. In eukaryotic cells, nutrients and growth factors regulate ribosomal RNA ...