They cloned large fragments of human chromosomes into a mitotically stable human minichromosome using Cre/LoxP-mediated translocation and telomere-directed truncation of the chromosome fragments ...
The Journal of Biological Chemistry 254 11495–11504 (1979). Bailis, J.M. et al. Minichromosome maintenance proteins interact with checkpoint and recombination proteins to promote S-phase genome ...