尽管过去三十多年的研究已经确立了哺乳动物雷帕霉素靶蛋白复合物1(mTORC1,由mTOR、RAPTOR和mLST8组成的复合体)作为最关键的营养物质感受器 ...
Participants in the Phase 2a study experienced rapid and meaningful decreases in depressive symptomsSuicidal ideation decreased by 80%SPN-820 was ...
Fernandes, Angelidaki et al. provide evidence supporting the spatial separation of mTORC1 activation and signalling. Differentially localized mTORC1 complexes phosphorylate distinct substrates in ...