Cordycepin, derived from fungi, shows promise in cancer therapy by inhibiting growth factor signaling pathways critical for ...

By blocking these actions, a class of drugs called mTOR inhibitors – of which rapamycin is one – can be used to treat cancer ...

Cancer Immunology Research publishes outstanding original articles reporting major advances in cancer immunology that span the discipline from basic investigations in host-tumor interactions to ...

Celcuity's lead asset, Gedatolisib, is a dual PI3K/mTOR inhibitor targeting various cancers, currently in multiple Phase 3 ...

Molecular Cancer Research publishes articles featuring novel, basic cancer research discoveries that prioritize broad molecular and cellular processes. Areas of emphasis include cell cycle and ...

Baking soda (sodium bicarbonate) does not prevent or cure cancer, but some research suggests it may help boost the effectiveness of conventional cancer treatments, such as chemotherapy. Baking soda is ...

Using breast cancer patient-derived organoids and tumor ... Key changes include reduced activity of mTOR, a metabolic regulator, and structural shifts in E-cadherin, a molecule involved in cell ...

PIK3CA gene encodes the p110α catalytic subunit of PI3K, which regulates the PI3K/AKT/mTOR signaling pathway. PIK3CA gene mutation is one of the most common mutations in colorectal cancer (CRC), ...

A brain tumor can be diagnosed using imaging tests that view the structure of the brain, along with a biopsy, which can carefully assess a sample of a suspected brain tumor under a microscope.

Aliad Biopharma Co. Ltd. has described compounds acting as autophagy inducers and mTOR complex 2 (mTORC2) inhibitors reported to be useful for the treatment of Alzheimer’s disease, among others. Aliad ...