Leptomeningeal inflammation in a mouse model of multiple sclerosis triggers deeply penetrating gene changes in underlying brain tissue, described using spatial transcriptomics.

This manuscript addresses infections of the parasite Taenia solium, which causes neurocysticercosis (NCC). NCC is a common parasitic infection that leads to severe neurological problems. It is a major ...

Researchers at the University of Freiburg have studied what happens immediately after a stroke in the stem cell niche known as the subventricular zone, using a mouse model. This revealed a ...

His lab first discovered that excitotoxicity might be a common pathophysiological process in sporadic ALS, which led to the use of the drug riluzole as a treatment for ALS. Rothstein made discoveries ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The mevalonate pathway produces essential ...

His lab first discovered that excitotoxicity might be a common pathophysiological process in sporadic ALS, which led to riluzole for ALS. Dr. Rothstein made discoveries on fundamental pathways that ...

A group of scientists say it's time to think differently about how to define and treat diseases such as Alzheimer's and multiple sclerosis. The question of what causes complex neurological ...