This important paper takes a novel approach to the problem of automatically reconstructing long-range axonal projections from stacks of images. The key innovation is to separate the identification of ...

Vigil Neuroscience, Inc. (Nasdaq: VIGL), a clinical-stage biotechnology company committed to harnessing the power of ...

A key to their investigation was to elucidate the critical involvement of microglia in axonal degeneration post-spinal cord axon injury. Microglia are primary immune cells in the central nervous ...

1 Central Washington University, Department of Physics, Ellensburg, WA, United States 2 Department of Integrative Biology, Michigan State University, East Lansing, MI, United States While the ...

This protective mechanism, dependent on the function of P2Y12 receptors, highlights a novel form of neuron-glia interaction that prevents acute axonal degeneration from spreading beyond the nodes.

The investigators added that inflammation and demyelination were reduced, while axonal density oligodendrocytes, ...

Mapping cell types in MS lesions reveals unique tissue niches and interactions, offering insights into the molecular drivers ...

The team of Dr Frédéric Charron, researcher at the Montreal Clinical Research Institute (IRCM) and professor at the Faculty of Medicine of the University of Montreal, has made a ...

"Enhanced axonal transport has been linked to neurodegenerative diseases like ALS and Alzheimer's disease," Cisterna and team ...

Nat Clin Pract Neurol. 2007;3(6):331-340. The finding of inflammatory lesions in PDN initially came as a surprise; however, it is now clear that complex relationships exist between obesity and ...